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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735336
Species: Mus musculus
RGD Object: Gene
Symbol: Akt1
Name: thymoma viral proto-oncogene 1
Acc ID: CHEBI:65769
Term: dieckol
Definition: A phlorotannin isolated from a brown alga Ecklonia cava which exhibits antioxidant, hepatoprotective and anticoagulant activities.
Chemical ID: MESH:C503840
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1decreases phosphorylationISOAKT1 (Homo sapiens)6480464CTDdieckol results in decreased phosphorylation of AKT1 proteinPMID:36683349
Akt1multiple interactionsISOAKT1 (Homo sapiens)6480464CTDdieckol results in decreased expression of and results in decreased phosphorylation of AKT1 proteinPMID:31291034
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