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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621168
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ogg1
Name: 8-oxoguanine DNA glycosylase
Acc ID: CHEBI:6570
Term: lupeol
Definition: A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables.
Chemical ID: MESH:C010480
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ogg1multiple interactionsISOOGG1 (Homo sapiens)6480464CTDlupeol inhibits the reaction [mancozeb results in decreased expression of OGG1 mRNA]PMID:27235710
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