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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737019
Species: Mus musculus
RGD Object: Gene
Symbol: Reg1
Name: regenerating islet-derived 1
Acc ID: CHEBI:6550
Term: loxtidine
Definition: A triazole that consists of 1,2,4-triazole bearing a methyl substituent at position 1, a hydroxymethyl substituent at position 3 and a {3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino group at position 5. A highly potent and selective H2-receptor antagonist.
Chemical ID: MESH:C039993
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Reg1decreases expressionEXP 6480464CTDloxtidine results in decreased expression of REG1 mRNAPMID:15940630
Reg1multiple interactionsEXP 6480464CTD[YF 476 co-treated with loxtidine] results in decreased expression of REG1 mRNAPMID:15940630
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