GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos3 | affects expression | EXP | | 6480464 | CTD | Losartan affects the expression of NOS3 mRNA | PMID:12198324 | Nos3 | increases expression | EXP | | 6480464 | CTD | Losartan results in increased expression of NOS3 mRNA | PMID:18971572 PMID:23091284 | Nos3 | increases phosphorylation | EXP | | 6480464 | CTD | Losartan results in increased phosphorylation of NOS3 protein | PMID:18390819 | Nos3 | multiple interactions | EXP | | 6480464 | CTD | [Losartan co-treated with Atorvastatin] results in increased expression of NOS3 mRNA; Losartan inhibits the reaction [Sodium Chloride results in decreased expression of NOS3 protein] | PMID:20232302 PMID:23091284 | |
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