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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557261
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1c19
Name: aldo-keto reductase family 1, member C19
Acc ID: CHEBI:65408
Term: andrographolide
Definition: A labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata that exhibits anti-HIV, anti-inflammatory and antineoplastic properties.
Chemical ID: MESH:C030419
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c19increases expressionEXP 6480464CTDandrographolide results in increased expression of AKR1C19 mRNA

PMID:19737545
Akr1c19multiple interactionsEXP 6480464CTD[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of AKR1C19 mRNA

PMID:19737545
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.