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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737354
Species: Homo sapiens
RGD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: CHEBI:65329
Term: LY294002
Definition: A chromone substituted with a phenyl group at position 8 and a morpholine group at position 2.
Chemical ID: MESH:C085911
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3multiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Histamine results in increased expression of F3]PMID:15020266 PMID:15371228 PMID:16009787
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