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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69273
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Socs2
Name: suppressor of cytokine signaling 2
Acc ID: CHEBI:6498
Term: lipoxin A4
Definition: A C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
Chemical ID: MESH:C040527
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Socs2increases expressionISORGD:13321666480464CTDlipoxin A4 results in increased expression of SOCS2 mRNA lipoxin A4 results in increased expression of SOCS2 protein

PMID:16415877
Socs2multiple interactionsISORGD:13321666480464CTDAHR affects the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA] butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA]

PMID:16415877
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