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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3283
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdgfb
Name: platelet derived growth factor subunit B
Acc ID: CHEBI:6498
Term: lipoxin A4
Definition: A C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
Chemical ID: MESH:C040527
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfbmultiple interactionsISORGD:7371246480464CTDlipoxin A4 affects the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein] PDGFB protein promotes the reaction [lipoxin A4 results in decreased phosphorylation of PDGFRB protein]

PMID:12223454 PMID:20709806
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