GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos2 | increases expression | ISO | Nos2 (Mus musculus) | 6480464 | CTD | Linuron results in increased expression of NOS2 mRNA | PMID:30661753 | Nos2 | multiple interactions | ISO | Nos2 (Mus musculus) | 6480464 | CTD | 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; [IL1B protein co-treated with TNF protein co-treated with Linuron] promotes the reaction [XBP1 protein binds to NOS2 promoter]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; SIGMAR1 gene mutant form inhibits the reaction [Linuron results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; XBP1 gene mutant form inhibits the reaction [Linuron results in increased expression of NOS2 mRNA] | PMID:30661753 | Nos2 | multiple interactions | ISO | NOS2 (Homo sapiens) | 6480464 | CTD | 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; STF 083010 inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]] | PMID:30661753 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |