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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736842
Species: Homo sapiens
RGD Object: Gene
Symbol: HTR2C
Name: 5-hydroxytryptamine receptor 2C
Acc ID: CHEBI:64629
Term: 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine
Definition: An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
Chemical ID: MESH:C015952
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HTR2Caffects bindingEXP 6480464CTD4-iodo-2,5-dimethoxyphenylisopropylamine binds to HTR2C proteinPMID:9857084
HTR2Cmultiple interactionsEXP 6480464CTD1-(8-bromobenzo(1,2-b;4,5-b')difuran-4-yl)-2-aminopropane inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine binds to HTR2C protein]PMID:9857084
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