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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631345
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg2
Name: ATP binding cassette subfamily G member 2
Acc ID: CHEBI:64629
Term: 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine
Definition: An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
Chemical ID: MESH:C015952
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg2increases activityISOABCG2 (Homo sapiens)6480464CTD4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of ABCG2 proteinPMID:30083819
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