GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | increases expression | EXP | | 6480464 | CTD | Isoproterenol results in increased expression of STAT3 mRNA | PMID:21335049 | Stat3 | multiple interactions | EXP | | 6480464 | CTD | STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]] | PMID:31712309 | Stat3 | affects localization | ISO | Stat3 (Rattus norvegicus) | 6480464 | CTD | Isoproterenol affects the localization of STAT3 protein | PMID:19299911 | Stat3 | increases expression | ISO | Stat3 (Rattus norvegicus) | 6480464 | CTD | Isoproterenol results in increased expression of STAT3; Isoproterenol results in increased expression of STAT3 protein | PMID:19299911 PMID:29355689 | Stat3 | increases phosphorylation | ISO | Stat3 (Rattus norvegicus) | 6480464 | CTD | Isoproterenol results in increased phosphorylation of STAT3 protein | PMID:25080425 | Stat3 | multiple interactions | ISO | Stat3 (Rattus norvegicus) | 6480464 | CTD | [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA; Betaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein]; Cyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]; Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein; Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein] | PMID:19299911 PMID:25080425 PMID:30303030 | Stat3 | multiple interactions | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol] | PMID:31712309 | |
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