GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases expression | EXP | | 6480464 | CTD | Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA | PMID:15302781 PMID:19023134 PMID:21335049 | Il1b | multiple interactions | EXP | | 6480464 | CTD | SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL1B]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL1B protein] | PMID:15302781 PMID:19023134 | Il1b | decreases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Isoproterenol results in decreased expression of IL1B mRNA; Isoproterenol results in decreased expression of IL1B protein | PMID:24286936 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Isoproterenol results in decreased expression of IL1B mRNA | PMID:32816093 | Il1b | increases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein | PMID:12215284 PMID:18487443 PMID:19904010 PMID:21762681 PMID:24286936 PMID:25045214 PMID:35014750 PMID:35305975 PMID:35430261 PMID:35815753 PMID:36593721 PMID:37806379 PMID:9387890 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein | PMID:24286936 | Il1b | multiple interactions | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | 5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]] | PMID:21762681 PMID:25045214 PMID:35305975 PMID:35430261 PMID:35815753 PMID:36593721 PMID:37806379 | |
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