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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604061
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL5
Name: C-C motif chemokine ligand 5
Acc ID: CHEBI:64294
Term: 7-ketocholesterol
Definition: A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.
Chemical ID: MESH:C003001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL5increases expressionEXP 6480464CTD7-ketocholesterol results in increased expression of CCL5 proteinPMID:24895526
CCL5multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [7-ketocholesterol results in increased expression of CCL5 protein]PMID:24895526
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