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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348646
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP3A5
Name: cytochrome P450 family 3 subfamily A member 5
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP3A5decreases expressionISOCyp3a9 (Rattus norvegicus)6480464CTDSodium Glutamate results in decreased expression of CYP3A9 mRNAPMID:20928830
CYP3A5multiple interactionsISOCyp3a13 (Mus musculus)6480464CTD[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP3A13 mRNA; [Sodium Glutamate co-treated with Tea] affects the expression of CYP3A13 mRNAPMID:25663641
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