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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733877
Species: Homo sapiens
RGD Object: Gene
Symbol: HADHA
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Acc ID: CHEBI:64227
Term: ciglitazone
Definition: An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
Chemical ID: MESH:C039671
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HADHAmultiple interactionsEXP 6480464CTD[ciglitazone binds to PPARG protein alternative form] which results in increased expression of HADHA mRNA; [ciglitazone binds to PPARG protein] which results in increased expression of HADHA mRNAPMID:16197558
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