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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10916
Species: Mus musculus
RGD Object: Gene
Symbol: Mpo
Name: myeloperoxidase
Acc ID: CHEBI:64163
Term: diquat
Definition: The organic cation formed formally by addition of an ethylene bridge between the nitrogen atoms of 2,2'-bipyridine. Most often available as the dibromide.
Chemical ID: MESH:D004178
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mpoincreases activityISOMpo (Rattus norvegicus)6480464CTDDiquat results in increased activity of MPO proteinPMID:15046732
Mpomultiple interactionsISOMpo (Rattus norvegicus)6480464CTDCapsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]PMID:15046732
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