Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:641
Term: N-methyl-4-phenylpyridinium
Definition: A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.
Chemical ID: MESH:D015655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3increases expressionEXP 6480464CTD1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 mRNAPMID:22776087
Ddit3affects expressionISODDIT3 (Homo sapiens)6480464CTD1-Methyl-4-phenylpyridinium affects the expression of DDIT3 mRNAPMID:12710931
Ddit3increases expressionISODdit3 (Rattus norvegicus)6480464CTD1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 mRNA; 1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 proteinPMID:12486162 PMID:16026605 PMID:24140863 PMID:28082123 PMID:28801915
Ddit3increases expressionISODDIT3 (Homo sapiens)6480464CTD1-Methyl-4-phenylpyridinium results in increased expression of DDIT3; 1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 mRNAPMID:12111836 PMID:14649730 PMID:17631803 PMID:19135031 PMID:24810058 PMID:25234470 PMID:27432061 PMID:28688763 PMID:32870474
Ddit3multiple interactionsISODdit3 (Rattus norvegicus)6480464CTDNicotine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 protein]; TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 protein]PMID:24140863 PMID:28082123
Ddit3multiple interactionsISODDIT3 (Homo sapiens)6480464CTDechinacoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3]; Plant Extracts inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 mRNA]; TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 protein]PMID:17631803 PMID:24140863 PMID:27432061
Go Back to source page   Continue to Ontology report