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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1608316
Species: Mus musculus
RGD Object: Gene
Symbol: Mir15b
Name: microRNA 15b
Acc ID: CHEBI:641
Term: N-methyl-4-phenylpyridinium
Definition: A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.
Chemical ID: MESH:D015655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir15bdecreases expressionISOMIR15B (Homo sapiens)6480464CTD1-Methyl-4-phenylpyridinium results in decreased expression of MIR15B mRNAPMID:29217406 PMID:30302821
Mir15bmultiple interactionsISOMIR15B (Homo sapiens)6480464CTDGSK3B protein inhibits the reaction [MIR15B mRNA inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP3 protein]]; MIR15B mRNA inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP3 protein]; SNHG1 protein inhibits the reaction [MIR15B mRNA inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP3 protein]]PMID:30302821
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