GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ins2 | multiple interactions | ISO | INS (Homo sapiens) | 6480464 | CTD | INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of IGF1R protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of INSR protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of IRS1 protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of IRS2 protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX mRNA]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NOS2 protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK1 protein]; INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK3 protein]; INS protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BCL2L2 mRNA] | PMID:26364587 | | ||||||||||||||||||||||
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