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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10691
Species: Mus musculus
RGD Object: Gene
Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Acc ID: CHEBI:64093
Term: 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine
Definition: An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Chemical ID: MESH:C044630
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c1multiple interactionsEXP 6480464CTDNR3C1 protein inhibits the reaction [1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine binds to SLC6A3 protein]PMID:11226678
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