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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736383
Species: Homo sapiens
RGD Object: Gene
Symbol: GLRX
Name: glutaredoxin
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GLRXincreases expressionEXP 6480464CTDtert-Butylhydroperoxide results in increased expression of GLRX mRNAPMID:12414654
GLRXmultiple interactionsISOGlrx (Rattus norvegicus)6480464CTD[GLRX protein co-treated with Glutathione] inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of OGDH protein]PMID:12680778
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