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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733019
Species: Homo sapiens
RGD Object: Gene
Symbol: PRDX2
Name: peroxiredoxin 2
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDtert-Butylhydroperoxide results in decreased expression of PRDX2 mRNA

PMID:15336504
increases expressionEXP 6480464CTDtert-Butylhydroperoxide results in increased expression of PRDX2 protein

PMID:11295360
decreases expressionISORGD:7354776480464CTDtert-Butylhydroperoxide results in decreased expression of PRDX2 mRNA

PMID:14729362
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.