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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62252
Species: Mus musculus
RGD Object: Gene
Symbol: Txnrd1
Name: thioredoxin reductase 1
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txnrd1increases expressionISOTXNRD1 (Homo sapiens)6480464CTDtert-Butylhydroperoxide results in increased expression of TXNRD1 mRNAPMID:12414654 PMID:16636651
Txnrd1multiple interactionsISOTXNRD1 (Homo sapiens)6480464CTDMT2A protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of TXNRD1 mRNA]PMID:16636651
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