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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559716
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ern1
Name: endoplasmic reticulum to nucleus signaling 1
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ern1multiple interactionsISOERN1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]]; ETFA mutant form inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]]; tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]PMID:24394546
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