GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ly96 | multiple interactions | ISO | LY96 (Homo sapiens) | 6480464 | CTD | 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [HMGB1 protein binds to LY96 protein binds to TLR4 protein]]; 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein binds to HMGB1 protein]]; 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein]]; 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [NOX4 protein binds to LY96 protein binds to TLR4 protein]]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased expression of CXCL8 mRNA]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased expression of IL1B mRNA]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased expression of IL6 mRNA]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased expression of NOX4 protein]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased expression of TNF mRNA]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased secretion of IL1B protein]; LY96 protein affects the reaction [tert-Butylhydroperoxide results in increased secretion of TNF protein]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of CASP3 protein modified form]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of CXCL8 mRNA]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of CXCL8 protein]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of ICAM1 mRNA]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of IL1B mRNA]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of IL1B protein]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of IL6 mRNA]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of PTGS2 mRNA]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased expression of VCAM1 mRNA]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein]; LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK9 protein]; tert-Butylhydroperoxide promotes the reaction [HMGB1 protein binds to LY96 protein binds to TLR4 protein]; tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein binds to HMGB1 protein]; tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein]; tert-Butylhydroperoxide promotes the reaction [NOX4 protein binds to LY96 protein binds to TLR4 protein] | PMID:28063877 PMID:29111459 | | ||||||||||||||||||||||
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