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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70498
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkb1
Name: nuclear factor kappa B subunit 1
Acc ID: CHEBI:64017
Term: (5Z,8Z,11Z,13E)-15-HETE
Definition: A HETE that is (5Z,8Z,11Z,13E)-15-hydroxyicosa-5,8,11,13-tetraenoic acid bearing a hydroxy substituent at position 15.
Chemical ID: MESH:C025984
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb1affects localizationISORGD:7308926480464CTD15-hydroxy-5 8 11 13-eicosatetraenoic acid affects the localization of NFKB1 protein

PMID:23355332
Nfkb1increases activityISORGD:7308926480464CTD15-hydroxy-5 8 11 13-eicosatetraenoic acid results in increased activity of NFKB1 protein

PMID:25600587
Nfkb1multiple interactionsISORGD:7308926480464CTDartemisinine inhibits the reaction [15-hydroxy-5 8 11 13-eicosatetraenoic acid affects the localization of NFKB1 protein]

PMID:23355332
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