Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2096
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alox5
Name: arachidonate 5-lipoxygenase
Acc ID: CHEBI:64017
Term: (5Z,8Z,11Z,13E)-15-HETE
Definition: A HETE that is (5Z,8Z,11Z,13E)-15-hydroxyicosa-5,8,11,13-tetraenoic acid bearing a hydroxy substituent at position 15.
Chemical ID: MESH:C025984
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alox5multiple interactionsISORGD:7327756480464CTD[benoxaprofen results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5 8 11 13-eicosatetraenoic acid [Masoprocol results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5 8 11 13-eicosatetraenoic acid [RS 43179 results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5 8 11 13-eicosatetraenoic acid [tenidap results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5 8 11 13-eicosatetraenoic acid

PMID:2849922
Go Back to source page   Continue to Ontology report