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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10510
Species: Mus musculus
RGD Object: Gene
Symbol: Egf
Name: epidermal growth factor
Acc ID: CHEBI:64017
Term: (5Z,8Z,11Z,13E)-15-HETE
Definition: A HETE that is (5Z,8Z,11Z,13E)-15-hydroxyicosa-5,8,11,13-tetraenoic acid bearing a hydroxy substituent at position 15.
Chemical ID: MESH:C025984
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases chemical synthesisISORGD:7368326480464CTDEGF protein results in increased chemical synthesis of 15-hydroxy-5, 8, 11, 13-eicosatetraenoic acid

PMID:15613483
multiple interactionsISORGD:7368326480464CTD15-hydroxy-5, 8, 11, 13-eicosatetraenoic acid promotes the reaction [EGF protein affects the localization of PRKCA protein]

PMID:15613483
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.