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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347802
Species: Homo sapiens
RGD Object: Gene
Symbol: MIR190A
Name: microRNA 190a
Acc ID: CHEBI:63952
Term: arsenic trichloride
Definition: A arsenic molecular entity that consists of a single arsenic atom bearing three chloro substituents.
Chemical ID: MESH:C050510
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR190Aincreases expressionEXP 6480464CTDarsenic trichloride results in increased expression of MIR190APMID:21750348
MIR190Amultiple interactionsEXP 6480464CTD[arsenic trichloride results in increased expression of MIR190A] promotes the reaction [[MIR190A binds to PHLPP1 3' UTR] which results in decreased expression of PHLPP1 protein]; [arsenic trichloride results in increased expression of MIR190A] promotes the reaction [[MIR190A binds to TP53INP1 3' UTR] which results in decreased expression of TP53INP1 protein]; [arsenic trichloride results in increased expression of MIR190A] which results in decreased expression of PHLPP1 proteinPMID:21750348
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