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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620634
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hr
Name: HR, lysine demethylase and nuclear receptor corepressor
Acc ID: CHEBI:63948
Term: trimethyltin
Definition: An organotin compound that consists of stannane in which three of the four hydrogens are substituted by methyl groups.
Chemical ID: MESH:C046488
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hraffects response to substanceISOHr (Mus musculus)6480464CTDHR protein affects the susceptibility to trimethyltinPMID:20886113
Hrmultiple interactionsISOHr (Mus musculus)6480464CTDHR protein affects the reaction [trimethyltin results in increased activity of CASP3 protein]PMID:20886113
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