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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620686
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Des
Name: desmin
Acc ID: CHEBI:63918
Term: artesunate
Definition: An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Chemical ID: MESH:C039726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Desdecreases expressionISORGD:13478876480464CTDArtesunate results in decreased expression of DES mRNA, Artesunate results in decreased expression of DES protein

PMID:30551460
Desmultiple interactionsISORGD:13478876480464CTDDeferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]

PMID:30551460
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