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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619826
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rpl6
Name: ribosomal protein L6
Acc ID: CHEBI:63918
Term: artesunate
Definition: An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Chemical ID: MESH:C039726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rpl6decreases response to substanceISORGD:7336946480464CTDRPL6 mRNA results in decreased susceptibility to artesunate

PMID:20144594
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