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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552222
Species: Mus musculus
RGD Object: Gene
Symbol: Tufm
Name: Tu translation elongation factor, mitochondrial
Acc ID: CHEBI:63918
Term: artesunate
Definition: An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Chemical ID: MESH:C039726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tufmdecreases response to substanceISOTUFM (Homo sapiens)6480464CTDTUFM mRNA results in decreased susceptibility to artesunatePMID:20144594
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