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RGD ID: 1308245
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Coq8a
Name: coenzyme Q8A
Acc ID: CHEBI:63918
Term: artesunate
Definition: An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Chemical ID: MESH:C039726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Coq8adecreases response to substanceISORGD:13438626480464CTDCOQ8A mRNA results in decreased susceptibility to artesunate

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