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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307184
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zbtb4
Name: zinc finger and BTB domain containing 4
Acc ID: CHEBI:63918
Term: artesunate
Definition: An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Chemical ID: MESH:C039726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zbtb4increases response to substanceISORGD:13162236480464CTDZBTB4 mRNA results in increased susceptibility to artesunate

PMID:20144594
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