Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


RGD ID: 1310890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgir
Name: prostaglandin I2 receptor
Acc ID: CHEBI:63916
Term: iloprost
Definition: A carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension.
Chemical ID: MESH:D016285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgiraffects bindingISORGD:13220526480464CTDIloprost binds to PTGIR protein

Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.