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RGD ID: 3438
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 synthase
Acc ID: CHEBI:6382
Term: Lasiocarpine
Definition: A pyrrolizine that has formula C21H33NO7.
Chemical ID: MESH:C005136
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgisdecreases expression ISOPTGIS (Homo sapiens)401959398RGD[Lasiocarpine cotreated with liver homogenate supernatant] decreases expression of PTGIS mRNA in vascular endothelial cells 
Ptgisdecreases expressionISOPTGIS (Homo sapiens)6480464CTDlasiocarpine metabolite results in decreased expression of PTGIS mRNA; lasiocarpine metabolite results in decreased expression of PTGIS proteinPMID:30465738
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