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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605371
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC47A1
Name: solute carrier family 47 member 1
Acc ID: CHEBI:63631
Term: topiramate
Definition: A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.
Chemical ID: MESH:C052342
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC47A1multiple interactionsEXP 6480464CTDtopiramate affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]PMID:22419765
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