Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620248
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb4
Name: ATP binding cassette subfamily B member 4
Acc ID: CHEBI:63628
Term: tipranavir
Definition: A pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor.
Chemical ID: MESH:C107201
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb4decreases activityISORGD:7369466480464CTDtipranavir results in decreased activity of ABCB4 proteinPMID:28437613
Go Back to source page   Continue to Ontology report