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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308964
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stac3
Name: SH3 and cysteine rich domain 3
Acc ID: CHEBI:63607
Term: linezolid
Definition: An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex.
Chemical ID: MESH:C098010
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stac3decreases expressionEXP 6480464CTDLinezolid results in decreased expression of STAC3 mRNAPMID:21296123
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