Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12244289
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: BIRC5
Name: baculoviral IAP repeat containing 5
Acc ID: CHEBI:63450
Term: masitinib
Definition: A member of the class of benzamides that is the carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine. It is a highly selective oral tyrosine kinase inhibitor.
Chemical ID: MESH:C526575
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BIRC5decreases expressionEXP 6480464CTDmasitinib results in decreased expression of BIRC5 mRNAPMID:22747577
Go Back to source page   Continue to Ontology report