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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Opa1
Name: OPA1, mitochondrial dynamin like GTPase
Acc ID: CHEBI:63041
Term: manganese(II) chloride
Definition: An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Chemical ID: MESH:C025340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Opa1decreases expressionISOOpa1 (Mus musculus)6480464CTDmanganese chloride results in decreased expression of OPA1 proteinPMID:34738708
Opa1multiple interactionsISOOpa1 (Mus musculus)6480464CTD6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of OPA1 protein]]; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of OPA1 protein]PMID:34738708
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