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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3214
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntrk3
Name: neurotrophic receptor tyrosine kinase 3
Acc ID: CHEBI:63041
Term: manganese(II) chloride
Definition: An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Chemical ID: MESH:C025340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntrk3multiple interactionsISONTRK3 (Homo sapiens)6480464CTDNTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein]PMID:31676349
Ntrk3multiple interactionsISONtrk3 (Mus musculus)6480464CTD[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein]PMID:31676349
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