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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735043
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myd88
Name: MYD88, innate immune signal transduction adaptor
Acc ID: CHEBI:62984
Term: zinc acetate
Definition: An acetate salt in which the cationic component is zinc(2+).
Chemical ID: MESH:D019345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myd88decreases expressionISOMYD88 (Homo sapiens)6480464CTDZinc Acetate results in decreased expression of MYD88 mRNAPMID:16357179
Myd88multiple interactionsISOMYD88 (Homo sapiens)6480464CTD[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of MYD88 mRNA; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]PMID:16357179 PMID:24080332
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