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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620283
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxo1
Name: forkhead box O1
Acc ID: CHEBI:62845
Term: 4-hydroxy-17beta-estradiol
Definition: A 4-hydroxy steroid that consists of 17beta-estradiol having an additional hydroxy group at position 4.
Chemical ID: MESH:C014036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7371556480464CTD4-hydroxyestradiol results in decreased expression of FOXO1 protein

PMID:23685341
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.