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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2750
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grpr
Name: gastrin releasing peptide receptor
Acc ID: CHEBI:6146
Term: kuwanone G
Definition: A tetrahydroxyflavone isolated from the root barks of Morus alba and has been shown to exhibit anti-inflammatory activity.
Chemical ID: MESH:C095194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7319606480464CTDkuwanon G binds to and results in decreased activity of GRPR protein, kuwanon G inhibits the reaction [GRP protein binds to GRPR protein]

PMID:7646517
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.