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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61862
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gria2
Name: glutamate ionotropic receptor AMPA type subunit 2
Acc ID: CHEBI:6121
Term: ketamine
Definition: A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Chemical ID: MESH:D007649
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gria2decreases expressionISOGria2 (Mus musculus)6480464CTDKetamine results in decreased expression of GRIA2 proteinPMID:31470060
Gria2multiple interactionsISOGria2 (Mus musculus)6480464CTDMAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein]PMID:31470060
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