Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	736886
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	HPGD
Name:	15-hydroxyprostaglandin dehydrogenase

Acc ID:	CHEBI:61076
Term:	belinostat
Definition:	A hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
Chemical ID:	MESH:C487081

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
HPGD	increases expression	EXP		6480464	CTD	belinostat results in increased expression of HPGD mRNA	PMID:26272509

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.