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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tc2n
Name: tandem C2 domains, nuclear
Acc ID: CHEBI:61076
Term: belinostat
Definition: A hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
Chemical ID: MESH:C487081
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tc2nincreases expressionISOTC2N (Homo sapiens)6480464CTDbelinostat results in increased expression of TC2N mRNAPMID:26272509
Tc2nmultiple interactionsISOTC2N (Homo sapiens)6480464CTD[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TC2N mRNAPMID:27188386
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